Rated 4.8/5 by hundreds of patients

Rated 4.8/5 by hundreds of patients

Topical antiviral

V-Cream

$46

A topical antiviral designed to help manage outbreaks by calming symptoms and supporting faster recovery.

Size

15 ml

30 ml

Takes 2 minutes • No charge unless approved

What you'll get

Personalized treatment plan designed for you

Convenient access to prescribed medications

Discreet, judgment-free care

What is V-Cream?

V-Cream is a compounded topical medication formulated with valacyclovir to help manage viral skin outbreaks such as HSV-1 and HSV-2. Instead of treating the body system-wide, it's applied directly to the affected area, allowing for targeted support right at the source. This localized approach offers a discreet, convenient option for people looking to address symptoms quickly and effectively.

How to use

• V-Cream can be applied as needed directly to the affected area. Before use, clean the area and your hands. Start with a small amount, and massage gently into the skin. Add more as needed, and wash your hands after application.
• The doctor will personalize your instructions to fit your unique needs. Details will be included in your shipment, if prescribed.
• Always reach out to your provider if you have any concerns or need assistance.

Potential side effects

• Side effects include redness, dryness, tingling, or mild irritation, but these are all typically mild and temporary. Contact your provider if you notice any side effects that bother you or don't go away.
• Prescription products require an online consultation to determine if a prescription is appropriate. We include regular follow-ups with your provider to monitor your response.

Only available by prescription from provider after virtual consultation. Product images are for illustrative purposes only and may include branding used for marketing. The actual medication you receive will be compounded and dispensed by a licensed partner pharmacy and labeled in accordance with pharmacy regulations. Compounded drugs are permitted to be prescribed under federal law but are not FDA-approved and do not undergo FDA safety, effectiveness, or manufacturing review. Individual results may vary.

Important safety information

Active ingredients: valacyclovir

This treatment may help to ease symptoms and reduce the severity and duration of outbreaks. Follow these instructions for best use and effectiveness:

follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed
apply at the earliest signs of breakout and reapply as needed
do not take by mouth. This medication is for topical treatment only
avoid contact with eyes
do not use on irritated skin or open wounds
wash your hands before and after applying formula. Store at room temperature away from moisture and heat. Keep the container tightly closed when not in use

Common side effects include:

headache
rash
itching
nausea
dizziness
skin reaction to sunlight

Tell your doctor if any of these symptoms are severe or do not go away.

Rare, but serious side effects:

symptoms of an allergic reaction: swelling of your face, lips, tongue or throat, severe rash or itching, very rapid heartbeat, problems breathing or swallowing, or fainting or feeling dizzy
severe irritation where applied: itching, burning, redness, swelling, blistering, or peeling skin with or without fever
other serious side effects: unusual hoarseness

If you experience any of these symptoms, stop taking the medication and call your doctor right away.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. You may also report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

It’s important to share your entire medical history with your provider. In particular, let your provider know if you have or have had:

human immunodeficiency virus infection (HIV)
acquired immunodeficiency syndrome (AIDS)
immunodeficiency
heart problems such as a heart attack, irregular heartbeat, angina, chest pain, narrowing of the aortic valve, or heart failure
heart surgery within the last 6 months, or plan to undergo heart surgery
seizure disorder
liver problems
kidney problems or are having kidney dialysis have any other medical conditions
allergic reactions to medications
are pregnant or breastfeeding

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medications, vitamins, and herbal and dietary supplements. Especially tell your provider if you take any of the following:

cladribine
clozapine
foscarnet
mycophenolate
talimogene laherparepvec
tenofovir Products
theophylline Derivatives
tizanidine
zidovudine

This treatment is not 100% effective for every patient. It may not work for every patient or may only work to partially resolve the condition that it is meant to treat. If the treatment is not working, or if you find that you are experiencing new or worsening symptoms, contact us as well as your doctor to identify if you should continue this treatment. If it is an emergency, call 911 or seek immediate medical help.

Who it's for

V-Cream is for individuals who want a localized, topical option to help manage viral skin outbreaks such as HSV-1 and HSV-2.

Active soresTingling sensationsItchingIrritationRednessRecurring outbreaks

Who it's for

V-Cream is for individuals who want a localized, topical option to help manage viral skin outbreaks such as HSV-1 and HSV-2.

Active soresTingling sensationsItchingIrritationRednessRecurring outbreaks

Why V-Cream?

V-Cream is designed to make outbreaks more manageable and less disruptive by focusing treatment exactly where symptoms appear.

Reduced discomfort

Faster healing

Targeted support

Subdues outbreaks

Why V-Cream?

V-Cream is designed to make outbreaks more manageable and less disruptive by focusing treatment exactly where symptoms appear.

Reduced discomfort

Faster healing

Targeted support

Subdues outbreaks

Using V-Cream

How it works

V-Cream works by interfering with viral replication at the application site. By applying the medication directly to the skin, it helps limit viral activity locally, which may reduce symptom severity and support faster healing. Early use—especially at the first sign of tingling or irritation—can help improve outcomes.

What to expect

When used as directed, many people notice reduced irritation and discomfort within the first few days of use. Results are often best when V-Cream is applied early, at the first sign of symptoms. Healing time can vary based on the severity of the outbreak and how quickly treatment is started.

Potential side effects

The most common side effects are usually mild and temporary, including redness, dryness, tingling, or irritation at the application site. Your provider will review your health history to help minimize potential risks and ensure the treatment is safe and effective for you.

Using V-Cream

How it works

What to expect

Potential side effects

Doctor-guided treatments designed for holistic wellness

50 Stars Health providers personalize care based on your individual health history, needs, and goals to support safe, effective treatment.

Dr. Gidon Akler, MD

Board-Certified in Medical Genetics & Genomics

Start treatment in 4 easy steps

Intake forms

2 minutes

Answer a few quick questions about your health history and goals.

Doctor review

Up to 2 days

A licensed provider will determine if the treatment is the right fit for you.

Order processing

5 business days

The order will be compounded, processed, and shipped, if prescribed.

Free standard shipping

3-5 days

Your treatment will ship quickly and discreetly to your door at no cost.

What our patients are saying

4.8 average rating

What our patients are saying

4.8 average rating

I liked having a topical option instead of just pills. No irritation for me, and it really helps with the itchy/tingly feelings.

Jasmine R.

Verified reviewer

Really smooth experience overall. The cream was simple to apply and I definitely noticed my outbreak healed faster than usual.

Danielle T.

Verified reviewer

The instructions were clear and shipping was fast. The cream absorbed quickly and I noticed a reduction in symptoms within a few minutes. Hard to say if it shortened the length of the outbreak.

Jim C.

Verified reviewer

I used V-Cream alongside 50 Stars Health's Valacyclovir tablets because I get constant, bad outbreaks, and I've never seen better results. So glad my provider recommended this treatment.

Suzanne W.

Verified reviewer

V-Cream was easy to use and felt gentle on my skin. I noticed improvement faster than I expected, and 50 Stars Health made the process very discreet.

Elena M.

Verified reviewer

Common questions about V-Cream

Visit our FAQ page for more

What conditions does V-Cream treat?

V-Cream is prescribed to help manage viral skin outbreaks, most commonly those caused by the herpes simplex virus (HSV). This includes outbreaks such as oral herpes (cold sores) and genital herpes, when appropriate.

How often can I apply V-Cream?

Most patients use it 2–4 times daily, depending on the severity of symptoms. Follow your provider's instructions for best results.

Will V-Cream permanently cure outbreaks?

No. V-Cream helps manage symptoms and outbreaks, but it does not cure viral infections.

Can I use V-Cream with other treatments?

In many cases, yes! V-Cream can be used alongside other treatments when appropriate. Some patients may benefit from combining topical treatment with our oral Valacyclovir tablets for more comprehensive outbreak management. Your provider can help determine whether using one or both options is the best approach based on your symptoms, frequency of outbreaks, and overall health.

Does V-Cream have an odor or taste?

Our V-Cream is formulated without any significant odor or flavor. Avoid consuming this cream beyond what is to be expected from proper cold sore treatment.

If eligible, how much does this treatment cost?

V-Cream is available on a one-time purchase basis. The price includes your initial consultation, follow-up visits, ongoing support, and standard shipping — with no hidden fees.

Your cost depends on which size container you choose:

15 mL - $50 per purchase
30 mL - $90 per purchase

Full billing terms and details

If prescribed, your treatment is an automatically renewing subscription. You'll be charged one day before each billing cycle begins.
Your plan includes a supply of your prescribed medication, shipped on a schedule based on your selected plan. Subscriptions renew automatically unless canceled—even if required actions to maintain an active prescription are not completed.
To avoid renewal, cancel at least 2 days before your next billing date. You can view your renewal date and manage or cancel your subscription anytime in your patient portal.
Cancellations take effect at the end of the current billing period. If applicable, you'll continue receiving your medication through the remainder of that paid cycle.
Refunds are not typically offered. However, partial refunds may be issued at our discretion for any non-dispensed portion of your subscription.

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